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Published on: April 19, 2022
Armentarium of topical hemostatic products in cardiovascular surgery: an update
Jessica Forcillo1, Louis P Perrault1
1Cardiac Surgery Department, Montreal Heart Institute, Université de Montréal, Canada.
Insights
Millions of surgeries annually face bleeding complications. This review covers current hemostatic products for cardiovascular surgery and discusses emerging topical agents to improve surgical hemostasis and patient outcomes.
Area of Science:
- Cardiovascular Surgery
- Surgical Complications
- Hemostasis
Background:
- Annually, 2.6 million in-hospital surgeries occur in Canada.
- Significant bleeding is the most common surgical complication, affecting up to 25% of procedures.
- Bleeding increases mortality, morbidity, transfusion needs, and causes hemodynamic instability.
Purpose of the Study:
- Review available hemostatic products in cardiovascular surgery.
- Update on new topical hemostatic agents in development.
- Optimize hemostasis during surgical procedures.
Main Methods:
- Literature review of hemostatic products.
- Analysis of current and emerging topical agents.
- Focus on cardiovascular surgical applications.
Main Results:
- Overview of the spectrum of hemostatic products used in cardiovascular surgery.
- Identification of novel topical hemostatic agents.
- Discussion of their potential impact on surgical bleeding.
Conclusions:
- Hemostatic products are crucial for managing surgical bleeding.
- New topical agents show promise for optimizing hemostasis.
- Continued innovation in hemostatic products is vital for improving surgical safety.
Abstract:
Within Canada, 2.6 million in-hospital surgical procedures are completed annually. Significant bleeding following is the most common surgical complication, occurring in up to 25% of all surgeries. Bleeding causes increased mortality and morbidity, by increasing the number of transfusions required, secondary to increased cumulative blood loss, and by causing hemodynamic instability. A solution to this issue encountered during surgery is the use of hemostatic products. The objectives of this manuscript are (1) to review the spectrum of hemostatic products available in cardiovascular surgery and (2) to provide an update on new topical products soon available, or in development, for optimizing hemostasis during surgical procedures.
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