Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Experimental Designs01:16

Experimental Designs

11.3K
An experimental design is a systematic process that allows researchers to evaluate the relationship between dependent and independent variables. There are three widely used types of experimental design - pre-experimental design, true experimental design, and quasi-experimental design. In pre-experimental design, the researcher compares the data before and after some interventions or treatments. The true-experimental design has more than one purposefully created group, a commonly measured...
11.3K
Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists01:30

Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists

926
Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function.
926
Role of Neurotransmitters in Memory01:23

Role of Neurotransmitters in Memory

2.8K
Neurotransmitters are integral to the brain's communication system, enabling neurons to transmit signals across synapses. This chemical exchange underpins various cognitive functions, including memory processes. The role of neurotransmitters in memory is multifaceted, influencing the encoding, consolidation, and retrieval of memories through their action on different neural circuits.
 Glutamate and Synaptic Plasticity
Glutamate, the brain's main excitatory neurotransmitter, is...
2.8K
Role of Cerebellum and Prefrontal Cortex in Memory01:14

Role of Cerebellum and Prefrontal Cortex in Memory

1.5K
The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the...
1.5K
Interference and Decay01:16

Interference and Decay

609
Forgetting is a complex cognitive phenomenon influenced by several factors, among which interference and decay are particularly prominent. These processes explain why individuals often struggle to retrieve specific information from memory, leading to lapses in recall that can be observed in everyday situations.
Interference occurs when competing memories hinder the retrieval of particular information. It can be classified into two types: proactive and retroactive interference. Proactive...
609
Blind Procedures02:07

Blind Procedures

10.8K
Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which...
10.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Finding the Right Fit: Caregiver and Clinician Perspectives on Intensive Treatment Schedules for Childhood Apraxia of Speech.

American journal of speech-language pathology·2026
Same author

Hydropersulfides promote angiogenesis and preserve vascular function.

Redox biology·2026
Same author

Correcting curvature in micromirror-based spatial light modulators with a microlens array.

Optics express·2026
Same author

Functional characterization of bat limb regulatory elements.

bioRxiv : the preprint server for biology·2026
Same author

Caregivers' Experiences of Assessment and Treatment for Their Child With Childhood Apraxia of Speech: An International Questionnaire Study.

American journal of speech-language pathology·2026
Same author

Interventions for childhood apraxia of speech.

The Cochrane database of systematic reviews·2026

Related Experiment Video

Updated: May 4, 2026

Eye Tracking, Cortisol, and a Sleep vs. Wake Consolidation Delay: Combining Methods to Uncover an Interactive Effect of Sleep and Cortisol on Memory
08:08

Eye Tracking, Cortisol, and a Sleep vs. Wake Consolidation Delay: Combining Methods to Uncover an Interactive Effect of Sleep and Cortisol on Memory

Published on: June 18, 2014

28.2K

Post-study caffeine administration enhances memory consolidation in humans.

Daniel Borota1, Elizabeth Murray1, Gizem Keceli2

  • 1Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, Maryland, USA.

Nature Neuroscience
|January 14, 2014
PubMed
Summary

Caffeine consumption may improve long-term memory consolidation in humans. This study found that caffeine enhanced memory performance after 24 hours, suggesting a positive impact on memory formation.

More Related Videos

Using Practice Testing, Public Speaking, and Source Monitoring to Examine the Influences of Learning Strategies and Stress on Episodic Memory
07:59

Using Practice Testing, Public Speaking, and Source Monitoring to Examine the Influences of Learning Strategies and Stress on Episodic Memory

Published on: June 14, 2019

10.3K
Experimental Protocol for Examining Behavioral Response Profiles in Larval Fish: Application to the Neuro-stimulant Caffeine
08:33

Experimental Protocol for Examining Behavioral Response Profiles in Larval Fish: Application to the Neuro-stimulant Caffeine

Published on: July 24, 2018

14.6K

Related Experiment Videos

Last Updated: May 4, 2026

Eye Tracking, Cortisol, and a Sleep vs. Wake Consolidation Delay: Combining Methods to Uncover an Interactive Effect of Sleep and Cortisol on Memory
08:08

Eye Tracking, Cortisol, and a Sleep vs. Wake Consolidation Delay: Combining Methods to Uncover an Interactive Effect of Sleep and Cortisol on Memory

Published on: June 18, 2014

28.2K
Using Practice Testing, Public Speaking, and Source Monitoring to Examine the Influences of Learning Strategies and Stress on Episodic Memory
07:59

Using Practice Testing, Public Speaking, and Source Monitoring to Examine the Influences of Learning Strategies and Stress on Episodic Memory

Published on: June 14, 2019

10.3K
Experimental Protocol for Examining Behavioral Response Profiles in Larval Fish: Application to the Neuro-stimulant Caffeine
08:33

Experimental Protocol for Examining Behavioral Response Profiles in Larval Fish: Application to the Neuro-stimulant Caffeine

Published on: July 24, 2018

14.6K

Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Pharmacology

Background:

  • The impact of caffeine on human long-term memory remains unclear.
  • Investigating caffeine's role in memory consolidation is crucial for understanding cognitive enhancement.

Purpose of the Study:

  • To determine if caffeine administration post-learning enhances long-term memory consolidation in humans.
  • To explore the dose-response relationship and specificity of caffeine's effects on memory processes.

Main Methods:

  • A behavioral discrimination task was employed to assess memory.
  • Caffeine was administered after the learning phase to isolate effects on consolidation.
  • Performance was evaluated 24 hours post-administration.

Main Results:

  • Caffeine administration significantly enhanced memory performance 24 hours later.
  • The enhancing effect followed an inverted U-shaped dose-response curve.
  • The observed benefits were specific to memory consolidation, not retrieval.

Conclusions:

  • Caffeine administration post-study effectively enhances the consolidation of long-term memories in humans.
  • The findings suggest a potential role for caffeine in improving memory persistence.
  • Further research can explore optimal dosages and applications for cognitive enhancement.