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Updated: May 4, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Management of the left atrial appendage
Sacha P Salzberg1, Herman Tolboom
1Department of Cardiovascular Surgery, University Hospital Zurich, CH-8091 Zurich, Switzerland.
Insights
Surgical and interventional left atrial appendage (LAA) occlusion offers alternatives to oral anticoagulation for preventing strokes in atrial fibrillation patients. This review details endocardial and epicardial LAA occlusion methods.
Area of Science:
- Cardiology
- Medical Device Technology
- Interventional Procedures
Background:
- Atrial fibrillation increases stroke risk.
- Oral anticoagulants are standard stroke prevention but have bleeding risks.
- Left atrial appendage (LAA) occlusion is an alternative therapy.
Purpose of the Study:
- To review current surgical and interventional approaches to LAA occlusion.
- To compare endocardial and epicardial LAA occlusion techniques.
- To provide a detailed overview of LAA occlusion procedures.
Main Methods:
- Review of existing literature on LAA occlusion.
- Detailed description of endocardial LAA occlusion techniques.
- Detailed description of epicardial LAA occlusion techniques.
Main Results:
- Both endocardial and epicardial approaches are viable for LAA occlusion.
- Specific device types and procedural steps vary between approaches.
- Literature supports the efficacy of LAA occlusion in stroke risk reduction.
Conclusions:
- LAA occlusion is an important alternative to oral anticoagulation for stroke prevention in atrial fibrillation.
- Understanding the nuances of endocardial and epicardial techniques is crucial for successful LAA exclusion.
- Further research may refine these techniques and expand their application.
Abstract:
Surgical and interventional exclusion left atrial appendage (LAA) are becoming important alternatives to oral anticoagulation for stroke prevention in the setting of atrial fibrillation. Herein we present the different approaches (endocardial vs. epicardial) to LAA occlusion. Each approach is depicted in detail and relevant literature is briefly presented.
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