Combined electrochemical/chemical methods for the synthesis and the molecular diversifying of isoindolinone-based
Laura Palombi1, Antonia Di Mola, Chiara Vignes
1Dipartimento di Chimica e Biologia, Università di Salerno, Via Giovanni Paolo II, 132-84084 , Fisciano, SA, Italy, lpalombi@unisa.it.
Abstract:
By means of C-H acids activation on Pt-cathode, an electrochemically initiated strategy aimed to developing a diversity-oriented synthesis based on the isoindolinone nucleus has been established. Conveniently, the achievement of a small library of new heterocycle-fused isoindolinone compounds with potential interest for drug design was carried out by using tandem reactions and one-pot sequential processes.
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