EUCAST technical note on Candida and micafungin, anidulafungin and fluconazole
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Updated: May 4, 2026

Whole Genome Sequencing of Candida glabrata for Detection of Markers of Antifungal Drug Resistance
Published on: December 28, 2017
Maiken Cavling Arendrup1, Manuel Cuenca-Estrella, Cornelia Lass-Flörl
1Unit of Mycology, Department of Microbiology & Infection Control, Statens Serum Institute, Copenhagen, Denmark.
Abstract:
The European Committee on Antimicrobial Susceptibility Testing Subcommittee on Antifungal Susceptibility Testing has determined breakpoints for micafungin and revised breakpoints for anidulafungin and fluconazole for Candida spp. This Technical Note is based on the corresponding rationale documents (http://www.eucast.org). The micafungin breakpoints are based on PK data, animal PK/PD data, microbiological data and clinical experience. The anidulafungin breakpoints for C. parapsilosis and fluconazole breakpoints for C. glabrata have been modified to species-specific values that categorise the wild-type as intermediate to accommodate use of these compounds in some clinical situations.
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