Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Potassium channel blockade induces rhythmic activity in a conditional burster neuron.

R M Harris-Warrick, B R Johnson

    Brain Research
    |July 28, 1987
    PubMed
    Summary

    Isolated lobster neurons (Anterior Burster or AB neurons) regain rhythmic bursting when potassium channel activity is reduced. This suggests that normally, potassium currents actively inhibit bursting in these neurons.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    A millimeter-wave photometric camera for long-range imaging through optical obscurants using kinetic inductance detectors.

    The Review of scientific instruments·2025
    Same author

    Erratum: "The Simons Observatory: Cryogenic half wave plate rotation mechanism for the small aperture telescopes" [Rev. Sci. Instrum. 95, 024504 (2024)].

    The Review of scientific instruments·2025
    Same author

    The Simons Observatory: Cryogenic half wave plate rotation mechanism for the small aperture telescopes.

    The Review of scientific instruments·2024
    Same author

    A scalable cryogenic LED module for selectively illuminating kinetic inductance detector arrays.

    The Review of scientific instruments·2022
    Same author

    Distributed physiology and the molecular basis of social life in eusocial insects.

    Hormones and behavior·2020
    Same author

    A large-diameter hollow-shaft cryogenic motor based on a superconducting magnetic bearing for millimeter-wave polarimetry.

    The Review of scientific instruments·2017

    Area of Science:

    • Neuroscience
    • Computational Neuroscience
    • Cellular Neuroscience

    Background:

    • The stomatogastric ganglion (STG) in lobsters controls feeding rhythms.
    • The Anterior Burster (AB) neuron is a key component of the STG.
    • Isolated AB neurons typically lose their rhythmic bursting activity.

    Purpose of the Study:

    • To investigate the ionic mechanisms underlying bursting in isolated AB neurons.
    • To identify factors that actively inhibit bursting in quiescent AB neurons.

    Main Methods:

    • Electrophysiological recordings from isolated AB neurons.
    • Pharmacological manipulation of potassium channel activity using specific compounds.

    Main Results:

    Related Experiment Videos

  • Compounds reducing potassium channel currents induced rhythmic bursting in isolated AB neurons.
  • This indicates that intrinsic conductances for bursting are present in quiescent AB neurons.

    • Conclusions:

    • Tonic potassium conductances actively inhibit the bursting capabilities of isolated AB neurons.
    • The AB neuron possesses the necessary intrinsic properties for bursting, which are normally suppressed.