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Related Concept Videos

Encephalitis l: Introduction01:19

Encephalitis l: Introduction

15
Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
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Arboviral Encephalitis01:25

Arboviral Encephalitis

59
Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
59
Encephalitis ll: Pathophysiology01:26

Encephalitis ll: Pathophysiology

22
Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...
22
Hemorrhagic Stroke ll: Pathophysiology01:29

Hemorrhagic Stroke ll: Pathophysiology

30
A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
30
Viral Meningitis01:18

Viral Meningitis

199
Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
199
Hemorrhagic Stroke l: Introduction01:17

Hemorrhagic Stroke l: Introduction

20
A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
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A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
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Varicella zoster encephalitis mimicking stroke.

Joaquín Valle Alonso1, Javier Fonseca1, Daniel López2

  • 1Department of Emergency Medicine, Hospital Valle de los Pedroches, Pozoblanco, Córdoba, Spain.

The American Journal of Emergency Medicine
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Physicians should consider diverse diagnoses for suspected stroke, as overdiagnosis is common. This case highlights varicella-zoster encephalitis as a rare but critical stroke mimic.

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Area of Science:

  • Neurology
  • Infectious Diseases

Background:

  • Stroke diagnosis requires a broad differential, as up to 31% of suspected cases are overdiagnosed.
  • Common stroke mimics include hypoglycemia and seizures, but numerous other conditions can present similarly.

Observation:

  • A 41-year-old presented with aphasia and right hemiparesis, symptoms often indicative of stroke.
  • Initial assessment strongly suggested an acute cerebrovascular event.

Findings:

  • The patient was ultimately diagnosed with varicella-zoster encephalitis.
  • This diagnosis underscores the importance of considering infectious etiologies in stroke-like presentations.

Implications:

  • Varicella-zoster encephalitis is a critical, albeit rare, differential diagnosis in patients with acute neurological deficits.
  • Broadening the diagnostic scope can prevent misdiagnosis and ensure timely, appropriate treatment for stroke mimics.