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Published on: August 17, 2022
Acute pancreatitis and hyperparathyroidism: a case series
Sudipta Dhar Chowdhury1, Reuben Thomas Kurien, Sandip Pal
1Department of Gastrointestinal Sciences, Christian Medical College, Vellore, 632 004, India, sudipto.d.c@gmail.com.
Primary hyperparathyroidism, a rare cause of acute pancreatitis, was studied in five patients. Early recognition of this metabolic condition is crucial for effective management and prevention of recurrent pancreatitis.
Area of Science:
- Endocrinology
- Gastroenterology
- Surgical Pathology
Background:
- Primary hyperparathyroidism is an uncommon metabolic cause of acute pancreatitis.
- This study investigates the link between primary hyperparathyroidism and acute pancreatitis.
Observation:
- Five consecutive patients presenting with acute or recurrent acute pancreatitis were identified.
- All patients exhibited elevated serum calcium and parathyroid hormone levels.
- Parathyroid adenoma was localized using ultrasonography and Sestamibi scanning.
Findings:
- Surgical removal of parathyroid adenoma (parathyroidectomy) was performed in four patients.
- Postoperative histology confirmed parathyroid adenoma in all surgically treated cases.
- One patient expired during treatment, highlighting potential complications.
Implications:
- Early diagnosis of primary hyperparathyroidism in pancreatitis patients is vital.
- Effective management can prevent recurrent episodes of acute pancreatitis.
- Metabolic causes, though rare, warrant consideration in pancreatitis etiology.
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