Reperfusion therapy for ST elevation acute myocardial infarction 2010/2011: current status in 37 ESC countries
Steen D Kristensen1, Kristina G Laut2, Jean Fajadet3
1Department of Cardiology, Aarhus University Hospital, Brendstrupgaardsvej 100, Skejby, DK-8200 Aarhus N, Denmark steendk@dadlnet.dk.
Insights
Primary percutaneous coronary intervention (PPCI) is the preferred reperfusion therapy for ST-elevation myocardial infarction (STEMI). This study found significant variations in PPCI use across European countries, with some regions undertreating STEMI patients.
Area of Science:
- Cardiology
- Interventional Cardiology
- Public Health
Background:
- Primary percutaneous coronary intervention (PPCI) is the gold standard reperfusion therapy for ST-elevation myocardial infarction (STEMI).
- Significant disparities in healthcare access and treatment modalities exist across European countries.
Purpose of the Study:
- To evaluate the contemporary use and types of reperfusion therapy for STEMI patients within European Society of Cardiology (ESC) member countries.
- To assess the variation in reperfusion strategies and PPCI availability across Europe.
Main Methods:
- A cross-sectional descriptive study utilizing aggregated country-level data from 37 ESC member countries for 2010-2011.
- Data collected on reperfusion therapy use, mortality, cardiologist numbers, and PPCI facility availability, supplemented by expert estimates where registries were absent.
Main Results:
- Wide variations in PPCI utilization were observed, ranging from 23 to 884 procedures per million inhabitants.
- PPCI was the dominant strategy in 33 countries, while thrombolysis was preferred in 4; 13 countries showed major increases in PPCI use since 2007.
- Significant disparities in the population served per PPCI center (24/7) were noted, from 31,300 to over 6.5 million inhabitants per center.
Conclusions:
- Substantial geographical variations in STEMI reperfusion treatment persist across Europe.
- Eastern and Southern European countries reported a considerable proportion of STEMI patients not receiving any reperfusion therapy.
- Encouraging the implementation of guideline-recommended reperfusion therapies is crucial to address these disparities.
Aims:
Primary percutaneous coronary intervention (PPCI) is the preferred reperfusion therapy in ST-elevation myocardial infarction (STEMI). We conducted this study to evaluate the contemporary status on the use and type of reperfusion therapy in patients admitted with STEMI in the European Society of Cardiology (ESC) member countries.
Methods And Results:
A cross-sectional descriptive study based on aggregated country-level data on the use of reperfusion therapy in patients admitted with STEMI during 2010 or 2011. Thirty-seven ESC countries were able to provide data from existing national or regional registries. In countries where no such registries exist, data were based on best expert estimates. Data were collected on the use of STEMI reperfusion treatment and mortality, the numbers of cardiologists, and the availability of PPCI facilities in each country. Our survey provides a brief data summary of the degree of variation in reperfusion therapy across Europe. The number of PPCI procedures varied between countries, ranging from 23 to 884 per million inhabitants. Primary percutaneous coronary intervention and thrombolysis were the dominant reperfusion strategy in 33 and 4 countries, respectively. The mean population served by a single PPCI centre with a 24-h service 7 days a week ranged from 31 300 inhabitants per centre to 6 533 000 inhabitants per centre. Twenty-seven of the total 37 countries participated in a former survey from 2007, and major increases in PPCI utilization were observed in 13 of these countries.
Conclusion:
Large variations in reperfusion treatment are still present across Europe. Countries in Eastern and Southern Europe reported that a substantial number of STEMI patients are not receiving any reperfusion therapy. Implementation of the best reperfusion therapy as recommended in the guidelines should be encouraged.
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