Reperfusion therapy for ST elevation acute myocardial infarction 2010/2011: current status in 37 ESC countries

Steen D Kristensen1, Kristina G Laut2, Jean Fajadet3

  • 1Department of Cardiology, Aarhus University Hospital, Brendstrupgaardsvej 100, Skejby, DK-8200 Aarhus N, Denmark steendk@dadlnet.dk.

European Heart Journal
|January 15, 2014
PubMed

Insights

Primary percutaneous coronary intervention (PPCI) is the preferred reperfusion therapy for ST-elevation myocardial infarction (STEMI). This study found significant variations in PPCI use across European countries, with some regions undertreating STEMI patients.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Public Health

Background:

  • Primary percutaneous coronary intervention (PPCI) is the gold standard reperfusion therapy for ST-elevation myocardial infarction (STEMI).
  • Significant disparities in healthcare access and treatment modalities exist across European countries.

Purpose of the Study:

  • To evaluate the contemporary use and types of reperfusion therapy for STEMI patients within European Society of Cardiology (ESC) member countries.
  • To assess the variation in reperfusion strategies and PPCI availability across Europe.

Main Methods:

  • A cross-sectional descriptive study utilizing aggregated country-level data from 37 ESC member countries for 2010-2011.
  • Data collected on reperfusion therapy use, mortality, cardiologist numbers, and PPCI facility availability, supplemented by expert estimates where registries were absent.

Main Results:

  • Wide variations in PPCI utilization were observed, ranging from 23 to 884 procedures per million inhabitants.
  • PPCI was the dominant strategy in 33 countries, while thrombolysis was preferred in 4; 13 countries showed major increases in PPCI use since 2007.
  • Significant disparities in the population served per PPCI center (24/7) were noted, from 31,300 to over 6.5 million inhabitants per center.

Conclusions:

  • Substantial geographical variations in STEMI reperfusion treatment persist across Europe.
  • Eastern and Southern European countries reported a considerable proportion of STEMI patients not receiving any reperfusion therapy.
  • Encouraging the implementation of guideline-recommended reperfusion therapies is crucial to address these disparities.
Abstract

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