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A Method for Screening and Validation of Resistant Mutations Against Kinase Inhibitors
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Enzalutamide and ruxolitinib
Susan A Hobson1, J Aubrey Waddell1, Dominic A Solimando1
1Dr. Hobson is a pharmacy practice resident (PGY1), Blount Memorial Hospital, Maryville, Tennessee.
Hospital Pharmacy
|January 15, 2014
Summary
This review covers essential aspects of cancer chemotherapy, focusing on the preparation, dispensing, and administration of antineoplastic therapy and agents. It aims to equip pharmacists with knowledge of complex regimens and toxic agents for treating malignant diseases.
Area of Science:
- Oncology Pharmacy
- Chemotherapy Agents
Background:
- Cancer chemotherapy involves complex regimens and highly toxic agents.
- Pharmacists require specialized knowledge for safe and effective patient care.
Purpose of the Study:
- To review key issues in the preparation, dispensing, and administration of antineoplastic therapy.
- To discuss commercially available and investigational agents used in cancer treatment.
Main Methods:
- Literature review and expert commentary on antineoplastic therapy.
- Discussion of practical considerations for oncology pharmacists.
Main Results:
- Highlights the complexities and toxicities associated with cancer chemotherapy.
- Identifies critical areas for pharmacist involvement in patient care.
Conclusions:
- Emphasizes the need for pharmacists to be well-versed in all facets of antineoplastic therapy.
- Provides a resource for addressing challenges in oncology pharmacy practice.
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