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Baló's concentric sclerosis: imaging findings and pathological correlation
Maxine Darke1, Farshad M Bahador2, Douglas C Miller3
1School of Medicine, University of Missouri, Columbia, MO, USA.
Journal of Radiology Case Reports
|January 15, 2014
Summary
Baló's concentric sclerosis, a rare variant of multiple sclerosis, presents unique concentric lesions. This case correlates MRI findings with biopsy-confirmed demyelination, enhancing diagnostic understanding.
Area of Science:
- Neurology
- Neuroimmunology
- Demyelinating Diseases
Background:
- Baló's concentric sclerosis (BCS) is a rare, distinct variant of multiple sclerosis (MS).
- BCS is characterized by alternating rings of demyelinated and myelinated axons.
- Diagnosis is often postmortem or via MRI without pathological confirmation.
Observation:
- A patient presented with left-sided focal sensorimotor deficits.
- Magnetic resonance imaging (MRI) revealed lesions consistent with BCS.
- A neoplastic process was initially suspected, prompting a surgical biopsy.
Findings:
- The surgical biopsy provided tissue for pathological diagnosis of demyelination.
- This case allowed for correlation between MRI findings and tissue diagnosis in BCS.
- Such direct clinicopathological correlations are infrequent in the literature.
Implications:
- This study enhances the understanding of BCS diagnostic criteria.
- Correlating imaging with pathology improves diagnostic accuracy for rare demyelinating diseases.
- This case highlights the importance of pathological confirmation in complex neurological presentations.
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