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Updated: May 4, 2026

Novel Methods for Intranasal Administration Under Inhalation Anesthesia to Evaluate Nose-to-Brain Drug Delivery
Published on: November 14, 2018
Intranasal midazolam may prevent gagging reflex: a case report
Meral Arslan Malkoc1, Necla Demir2, Zehra Ileri3
1Department of Prosthodontics, Faculty of Dentistry, İnönü University, Malatya Turkey.
Intranasal midazolam effectively suppressed exaggerated gag reflexes in dental patients, enabling successful impressions. This method offers a safe and rapid solution for managing gagging during dental procedures.
Area of Science:
- Dentistry
- Pharmacology
Background:
- Exaggerated gag reflex complicates dental treatment.
- Report on three patients with hypersensitive gag reflexes.
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