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Related Concept Videos

Autoimmune Disorders01:29

Autoimmune Disorders

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Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
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Introduction to Innate and Adaptive Immunity01:21

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The human immune system is a complex defense mechanism that protects the body from harmful pathogens and foreign substances. It comprises two crucial components: innate and adaptive immunity.
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Special Features of Adaptive Immunity01:20

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The adaptive immune system, a crucial component of the overall immune response, offers a highly specialized defense against pathogens. It involves specific cell types and features, enabling it to combat infections effectively and efficiently.
The primary cell types involved in adaptive immunity are T cells and B cells. Each type has a unique role in defending the body against pathogens. T cells are responsible for cell-mediated immunity. They identify and eliminate infected cells directly,...
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Antigens Involved in Adaptive Immunity01:26

Antigens Involved in Adaptive Immunity

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An antigen is any substance the immune system identifies as foreign and potentially harmful to the body, prompting an immune response. Antigens have two functional properties: immunogenicity and reactivity. Immunogenicity is the ability of an antigen to stimulate a specific immune response. At the same time, reactivity describes the antigen's ability to react with the cells and antibodies produced in response to it.
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Interrogating Individual Autoreactive Germinal Centers by Photoactivation in a Mixed Chimeric Model of Autoimmunity
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In this issue: autoimmunity and innate immunity.

Adrian Bot1

  • 1Editor-in-Chief, International Reviews of Immunology, Vice President, Scientific Affairs, Kite Pharma, Inc., Santa Monica, CA, USA.

International Reviews of Immunology
|January 16, 2014
PubMed
Summary

This collection explores innate immunity and inflammatory diseases, including pyroptosis, celiac disease, colitis treatments, and the role of IL-18 gene polymorphism in RA and SLE.

Area of Science:

  • Immunology
  • Inflammatory Diseases

Background:

  • Innate immunity plays a crucial role in host defense and inflammatory responses.
  • Dysregulation of innate immunity is implicated in various autoimmune and inflammatory conditions.

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