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Outcomes of open surgical repair for chronic type B aortic dissections
Allan M Conway1, Mostafa Sadek1, Joanelle Lugo1
1Lenox Hill Heart and Vascular Institute of New York, Lenox Hill Hospital, North Shore-LIJ Health System, New York, NY.
Insights
Open surgical repair (OSR) for chronic type B aortic dissection (CTBAD) is a durable treatment with low mortality. High-risk patients may benefit from further evaluation for thoracic endovascular aortic repair (TEVAR).
Area of Science:
- Cardiovascular Surgery
- Vascular Surgery
- Thoracic Surgery
Background:
- Open surgical repair (OSR) for chronic type B aortic dissection (CTBAD) carries significant risks.
- The efficacy of thoracic endovascular aortic repair (TEVAR) for CTBAD remains uncertain.
- Identifying high-risk CTBAD patients is crucial for treatment selection.
Purpose of the Study:
- To analyze the outcomes of OSR in CTBAD patients.
- To identify predictors of mortality and complications after OSR for CTBAD.
- To evaluate the suitability of OSR as a durable option for CTBAD.
Main Methods:
- Retrospective analysis of 221 patients undergoing thoracic or thoracoabdominal aortic aneurysm repair from 1999-2010.
- Focus on 86 patients with CTBAD treated with OSR.
- Data collected included mortality, complications, length of stay, and reinterventions.
Main Results:
- Hospital mortality was 5.8% for OSR in CTBAD.
- Major complications included paraplegia, stroke, and renal failure (2.3% each).
- Overall survival at 7 years was 70%, with 86% freedom from reoperation.
Conclusions:
- OSR is a durable treatment for CTBAD with acceptable mortality rates.
- Redo operations and prolonged cardiopulmonary bypass time were predictors of mortality.
- Further evaluation is needed to determine optimal treatment strategies, including TEVAR, for high-risk CTBAD patients.
Objective:
Open surgical repair (OSR) for chronic type B aortic dissection (CTBAD) has an associated morbidity and mortality. The role of thoracic endovascular aortic repair (TEVAR) in CTBAD has not been determined. We analyzed our contemporary experience of CTBAD undergoing OSR to identify high-risk patients who may be considered for TEVAR.
Methods:
From 1999 to 2010, 221 patients had repair of descending thoracic and thoracoabdominal aortic aneurysms, including 86 patients with CTBADs. We analyzed this cohort for mortality, complications, length of stay, and reinterventions.
Results:
OSR was performed in 25 (29%) and 61 (71%) patients for descending thoracic and thoracoabdominal CTBAD, respectively. Median age was 57.0 years (interquartile range [IQR], 52.0-64.2 years), and median diameter was 6.0 cm (IQR, 5.0-6.9 cm). Fifty-nine patients (69%) were male. Eight (9%) were treated for rupture. Follow-up duration was 4.6 years (IQR, 2.8-6.9 years). Hospital mortality occurred in five patients (5.8%). Cardiopulmonary bypass was used in 83 patients (97%) and deep hypothermic arrest in 36 (42%). Two patients (2.3%) each developed paraplegia, stroke, and renal failure requiring permanent hemodialysis in the postoperative period. Length of stay was 13.5 days (IQR, 10.0-21.0 days). Univariate predictors of hospital death included redo operations and prolonged pump time (P < .05). Six patients (7%) had aortic-related reoperations at 4.3 years (IQR, 2.7-5.2 years): one for an ascending aortic aneurysm and five for descending aortic aneurysms. Overall survival at 1, 5, and 7 years was 92%, 83%, and 70%, respectively, and freedom from reoperation was 99%, 90%, and 86%, respectively.
Conclusions:
OSR of CTBAD is a durable option with low mortality. Patients requiring redo operations or anticipated prolonged pump time need further evaluation to determine whether conventional OSR or TEVAR, if feasible, is the optimal treatment option.
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