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Updated: May 4, 2026

The Measurement and Treatment of Suppression in Amblyopia
Published on: December 14, 2012
Positional suppression of periodic alternating nystagmus
Seok Jong Chung1, Seong-Ho Park, Ji-Soo Kim
1Department of Neurology (SJC), Yonsei University College of Medicine, Seoul, Korea; Department of Neurology (S-HP, J-SK, SWO, HJK, JHP, YEH), Seoul National University Bundang Hospital, Seongnam-si, Korea; and Department of Neurology (S-HP, J-SK), Seoul National University College of Medicine, Seoul, Korea.
Abstract:
A 43-year-old man with a high-grade glioma involving the cerebellar nodulus showed a near-complete suppression of periodic alternating nystagmus (PAN) in the lateral decubitus position to either side. This positional modulation of PAN is consistent with suppression of the velocity storage mechanism by head position changes (tilt dumping) and is supportive of the role of the velocity storage mechanism in generating PAN.
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