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Primary biliary cirrhosis and auto immune hepatitis overlap syndrome mimicking cholangiocarcinoma
A Adel1, Z Zamri, A Azlanuddin
1Department of Surgery, Universiti Kebangsaan Malaysia Medical Centre (UKMMC), Jalan Yaakob Latif, 56000 Bandar Tun Razak, Cheras, Kuala Lumpur, Malaysia.
Abstract:
Primary Biliary Cirrhosis (PBC) and Auto Immune Hepatitis (AIH) are autoimmune diseases of the liver which highlighted with slow destructive process of intra hepatic small bile ducts. As a result of these damages cholestasis and over the time tissue damage will happen, which leads to scarring, fibrosis and finally cirrhosis. Some patients may present with clinical and biochemical features of both conditions, which is called "Overlap syndrome". Here we are reporting a case of PBC-AIH overlap syndrome that primarily diagnosed as gallbladder carcinoma and went under operation and finally histological examination revealed to be PBC.
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