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Updated: May 4, 2026

Multi-parameter Measurement of the Permeability Transition Pore Opening in Isolated Mouse Heart Mitochondria
Published on: September 7, 2012
Changes in the permeability of the inner mitochondrial membrane associated with plastid development
1Department of Biological Sciences, University of Lancaster, LA1 4YQ, Lancaster, UK.
Abstract:
Mitochondria isolated from greening etiolated laminae of Avena sativa L. show changes in the permeability of their inner membranes during chloroplast development similar to those described earlier for plastids. Oxalo-acetate, succinate and α-keto-glutarate permeate most readily inner membranes of mitochondria isolated from laminae given 2 h illumination whilst glutamate and glycine show later and more general penetration into the matrix spaces of mitochondria from greening tissue. Aminolevulinic acid (ALA) by contrast does not readily enter Avena mitochondria especially those isolated from laminae illuminated for longer than 2 h.
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