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The use of platelet-rich plasma gel in patients with mixed tumour undergoing superficial parotidectomy: a randomized
Marco Scala1, Paola Mereu, Francesco Spagnolo
1S.C. Chirurgia Plastica e Ricostruttiva, IRCCS San Martino - IST, L.go R. Benzi, 10, 16132 Genoa, Italy. francesco.spagnolo85@gmail.com.
Background/Aim:
Salivary gland tumors are mostly benign tumors. Whether a more conservative surgical approach at greater risk of recurrence, or a more radical intervention with an increased risk of facial paralysis is warranted is still under discussion. Our study addresses the opportunity for improving surgical outcome by employing platelet-rich plasma (PRP) gel at the surgical site.
Patients And Methods:
Twenty consecutive patients undergoing superficial parotidectomy were randomized and assigned to two groups, one with and one without PRP gel. Many parameters were evaluated after surgery and during follow-up, such as the duration of hospitalization, facial nerve deficit, onset of Frey's syndrome, relapse, cosmetic results, presence of keloid or scar depressions, behavior of several facial muscles.
Results:
Our explorative analysis suggests a positive effect of PRP on surgical outcome in patients undergoing parotidectomy, whereas no negative effects were detected.
Conclusion:
This work suggests that administration of PRP in patients undergoing parotidectomy is beneficial.
