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Myxoglobulosis of appendix a rare entiy

Biren Prasad Padhy1, Sarat Kumar Panda1

  • 1Department of surgery, IMS & SUM Hospital K8 Kalinganagar, 137/N4 IRC Village, Bhubaneswar, 751015 Orissa India.

The Indian Journal of Surgery
|January 16, 2014
PubMed

Insights

A rare case of appendiceal myxoglobulosis was diagnosed in an 18-year-old male. Microscopic analysis revealed mucin-filled globules, leading to a diagnosis of myxoglobulosis due to mucosal hyperplasia and obstruction.

Area of Science:

  • Gastroenterology
  • Pathology
  • Surgical Case Reports

Background:

  • Myxoglobulosis is an extremely rare appendiceal condition.
  • Appendiceal pathologies can present with varied and sometimes confusing clinical symptoms.

Purpose of the Study:

  • To report a unique case of appendiceal myxoglobulosis.
  • To highlight diagnostic challenges and microscopic findings.

Main Methods:

  • Laparoscopic appendectomy was performed for suspected recurrent appendicitis.
  • Gross examination revealed extrusion of numerous whitish, egg-like globules.
  • Microscopic examination with histochemical mucin stains confirmed the nature of the globules.

Main Results:

  • The appendix contained numerous mucin-filled globules (0.2-0.7 cm).
  • Initial misdiagnosis as appendiceal hydatid cyst occurred.
  • Microscopic findings confirmed myxoglobulosis, characterized by mucin laminations and an amorphous core.
  • Associated mucosal hyperplasia and luminal obstruction were noted.

Conclusions:

  • Appendiceal myxoglobulosis is a rare differential diagnosis for appendiceal masses.
  • Accurate histopathological examination is crucial for diagnosis.
  • Mucosal hyperplasia and luminal obstruction are implicated in its pathogenesis.
Keywords:
Laparoscopic appendicetomyMembraneMucoceleMyxoglobulosis

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