MR-less surface-based amyloid assessment based on 11C PiB PET.

Luping Zhou1, Olivier Salvado2, Vincent Dore2

  • 1CSIRO Preventative Health Flagship, CSIRO Computational Informatics, The Australian e-Health Research Centre, Herston, Australia ; Department of Computer Science and Software Engineering, University of Wollongong, Wollongong, Australia.

Plos One
|January 16, 2014
PubMed
Summary

This study developed a novel PET-only method to quantify beta-amyloid (Aβ) burden in Alzheimer's disease (AD) without MRI. The MR-less approach shows high accuracy, offering a valuable tool for Aβ imaging when MRI is unavailable.