Related Experiment Video

Updated: May 4, 2026

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
23:06

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis

Published on: August 11, 2008

18.4K

Modifiable risk factors associated with tuberculosis disease in children in Pune, India

J Jubulis1, A Kinikar2, M Ithape3

  • 1Johns Hopkins University, Baltimore, Maryland, USA; Maine Medical Center, Portland, Maine, USA.

The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease
|January 17, 2014
PubMed

Insights

Household TB exposure, food insecurity, and indoor air pollution (IAP) are linked to pediatric TB in India. Vitamin D deficiency was not found to be a significant risk factor in this study.

Area of Science:

  • Public Health
  • Pediatric Infectious Diseases
  • Environmental Health

Background:

  • India bears the world's largest tuberculosis (TB) burden, representing 26% of global cases.
  • Understanding risk factors for pediatric TB is crucial for targeted interventions.

Purpose of the Study:

  • To investigate the association between novel modifiable risk factors and TB in Indian children.
  • To assess the role of indoor air pollution (IAP) and vitamin D deficiency in pediatric TB.

Main Methods:

  • A case-control study involving children aged ≤ 5 years.
  • Logistic regression was used to analyze associations with TB, including IAP and vitamin D deficiency.
  • Two case definitions for pediatric TB were applied.

Main Results:

  • Household TB exposure, food insecurity, and IAP were significantly associated with pediatric TB.
  • Vitamin D deficiency was not found to be significantly associated with TB.
  • Associations remained significant after applying a consensus research definition for pediatric TB.

Conclusions:

  • Household TB exposure, IAP, and food insecurity are independent risk factors for pediatric TB in India.
  • These findings highlight key modifiable factors for TB prevention strategies in children.
Abstract

More Related Videos

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates10:04

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Published on: September 5, 2017

17.1K
A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection10:10

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection

Published on: October 5, 2015

19.9K

Related Concept Videos

Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
1.7K
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
828
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
1.8K
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
1.0K
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
2.5K
Factors Affecting Illness01:18

Factors Affecting Illness

When a person's physical, emotional, intellectual, social development or spiritual functioning is compromised, this deviation from a healthy normal state is called illness. Illness creates stress that in turn harms individuals. Irritation, anger, denial, hopelessness, and fear are behavioral and emotional changes an individual experiences in the phases of illness. A variety of factors influence a person's health and well-being.
For instance, risk factors are connected to illness,...
5.4K