Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Scleroderma after occupational exposure to trichlorethylene and trichlorethane.

H Flindt-Hansen, H Isager

    Acta Dermato-Venereologica
    |January 1, 1987
    PubMed
    Summary

    Occupational exposure to trichlorethylene and trichlorethane may be linked to developing scleroderma. This study explores the potential etiological role of these chlorohydrocarbon solvents in three reported cases.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [Oxygen transport and pregnancy].

    Ugeskrift for laeger·1998
    Same author

    Extra-intestinal amebiasis: clinical presentation in a non-endemic setting.

    Scandinavian journal of infectious diseases·1993
    Same author

    Photocarcinogenesis in mice and the effect of a sunscreen, para-aminobenzoic acid.

    Danish medical bulletin·1992
    Same author

    Impact of the 1987 revised AIDS case definition in Denmark: a follow-up study 2 years after its adoption.

    Scandinavian journal of infectious diseases·1992
    Same author

    Ultraviolet light induction of peripheral granulocytosis with splenomegaly: protection of mice with topical p-aminobenzoic acid (PABA).

    The British journal of dermatology·1991
    Same author

    [HIV-positive persons in a Danish provincial region 1985-1990].

    Ugeskrift for laeger·1991

    Area of Science:

    • Toxicology
    • Dermatology
    • Occupational Medicine

    Background:

    • Scleroderma is a chronic autoimmune disease characterized by hardening and tightening of the skin.
    • Occupational exposures to various chemicals have been implicated in the development of autoimmune conditions.
    • Chlorohydrocarbon solvents are widely used in industrial settings.

    Observation:

    • Three cases of scleroderma are presented.
    • All three patients had a history of occupational exposure to trichlorethylene and trichlorethane.
    • The onset of scleroderma symptoms occurred after the period of solvent exposure.

    Findings:

    • The described cases suggest a potential association between occupational exposure to trichlorethylene and trichlorethane and the development of scleroderma.
    • Further investigation is warranted to establish a definitive etiological link.

    Implications:

    • Identifying specific occupational exposures as etiological factors for scleroderma can inform preventative measures.
    • This research highlights the importance of evaluating environmental and occupational histories in patients with scleroderma.
    • Understanding solvent toxicity is crucial for protecting worker health and preventing occupational diseases.

    Related Experiment Videos