Dermoscopic findings in cutaneous metastases
Karen A Chernoff1, Ashfaq A Marghoob2, Mario E Lacouture3
1Department of Dermatology, Weill Cornell Medical College, New York, New York.
JAMA Dermatology
|January 17, 2014
Summary
Dermoscopy reveals vascular patterns in most cutaneous metastases, aiding diagnosis. Pigmented lesions in cancer patients without melanoma history may indicate breast cancer metastasis.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Cutaneous metastases are rare but prognostically significant.
- Dermoscopy is valuable for skin lesion assessment, but data on cutaneous metastases are limited.
Purpose of the Study:
- To describe dermoscopic findings in cutaneous metastases.
- To correlate dermoscopic features with clinical and histological data.
- To assess the utility of dermoscopy in diagnosing skin metastases.
Main Methods:
- Review of high-quality dermoscopic images from 20 outpatients with biopsy-proven cutaneous metastases.
- Correlation of dermoscopic findings with clinical and histological data.
- Analysis of lesion characteristics including color, vascular patterns, and pigmentation.
Main Results:
- Most nonpigmented lesions (17/20) showed vascular patterns, predominantly serpentine vessels.
- Pink homogeneous structureless areas were observed in 12% of nonpigmented lesions.
- Pigmented lesions (3/20), all metastatic breast carcinoma, displayed various melanocytic patterns.
Conclusions:
- Visible vascular structures on dermoscopy suggest cutaneous metastasis in cancer patients.
- Pigmentation in such lesions, without melanoma history, points to primary breast carcinoma.
- Dermoscopy aids in evaluating suspected skin metastases and lesions of unknown origin in cancer patients.
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