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Intravenous iron in postpartum anemia
Geeta Jain1, Urmila Palaria2, S K Jha3
1Department of O&G, Govt. Medical College, Haldwani, Rampur Road, Haldwani, Uttarakhand India.
Journal of Obstetrics and Gynaecology of India
|January 17, 2014
Summary
Intravenous iron-sucrose rapidly increases hemoglobin levels in postpartum anemia compared to oral ferrous fumarate. This study found IV iron-sucrose to be more effective for treating postpartum anemia.
Area of Science:
- Obstetrics and Gynecology
- Hematology
- Pharmacology
Background:
- Postpartum anemia is a common complication affecting maternal health.
- Oral iron supplementation is the standard treatment but can be slow to improve hemoglobin levels.
Purpose of the Study:
- To compare the effectiveness of intravenous iron-sucrose versus oral ferrous fumarate in treating postpartum anemia.
- To evaluate the rate of hemoglobin increase in women with postpartum anemia receiving different iron formulations.
Main Methods:
- A randomized study involving 40 women with postpartum anemia (hemoglobin < 8 g/dl).
- Group I received intravenous iron-sucrose (300-600 mg) over 3 days.
- Group II received oral ferrous fumarate (300 mg daily) for 14 days.
Main Results:
- Intravenous iron-sucrose group showed a mean hemoglobin increase of 2.4 g/dl by day 14.
- Oral ferrous fumarate group showed a mean hemoglobin increase of 1.2 g/dl by day 14.
- Significantly higher mean hemoglobin values were observed in the IV iron-sucrose group on days 7 and 14 (p < 0.001).
Conclusions:
- Intravenous iron-sucrose is a more effective and rapid treatment for postpartum anemia compared to oral ferrous fumarate.
- Intravenous iron-sucrose administration led to a faster increase in hemoglobin levels without serious adverse events.
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