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Keratitis caused by Aspergillus pseudotamarii

Nikolett Baranyi1, Sándor Kocsubé1, András Szekeres1

  • 1Department of Microbiology, Faculty of Science and Informatics, University of Szeged, Közép fasor 52, H-6726 Szeged, Hungary.

Medical Mycology Case Reports
|January 17, 2014
PubMed

Insights

A fungal eye infection caused by Aspergillus pseudotamarii was successfully treated with topical natamycin. This specific fungus also produced harmful aflatoxins, highlighting a potential dual threat.

Area of Science:

  • Ophthalmology
  • Mycology
  • Infectious Diseases

Background:

  • Fungal keratitis is a serious ocular infection that can lead to vision loss.
  • Accurate identification of fungal pathogens is crucial for effective treatment.

Purpose of the Study:

  • To report a case of fungal keratitis caused by Aspergillus pseudotamarii.
  • To describe the successful treatment and etiological investigation of the infection.

Main Methods:

  • Clinical presentation and treatment of a patient with fungal keratitis.
  • Polyphasic approach including morphological and molecular techniques for fungal identification.
  • Analysis of aflatoxin production by the isolated fungus.

Main Results:

  • A male patient experienced redness, pain, and vision defects in the left eye.
  • Topical natamycin treatment resulted in complete healing of the corneal infiltrate within two weeks.
  • The causative agent was identified as Aspergillus pseudotamarii, a producer of aflatoxins.

Conclusions:

  • Aspergillus pseudotamarii can cause fungal keratitis.
  • Topical natamycin is an effective treatment for this condition.
  • The identification of aflatoxin production by this isolate warrants further investigation.
Keywords:
AflatoxinsAspergillus pseudotamariiCorneal ulcerFungal keratitisKeratomycosis

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