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Author Spotlight: Advancements in Understanding and Combatting Shigella Infections
Published on: February 9, 2024
Simultaneous infection with Shigella sonnei and Vibrio cholerae in a young child
1Clinical Laboratory Sciences Program, Department of Pharmacy Administration and Allied Health Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY 11365, USA. hochstel@stjohns.edu
Insights
A pediatric case of infectious diarrhea in an infant was caused by concurrent Shigella sonnei and Vibrio cholerae infections. This highlights the crucial role of microbiology labs in identifying rare enteric pathogens.
Area of Science:
- Microbiology
- Infectious Diseases
- Pediatrics
Background:
- Infectious diarrhea is a common pediatric illness.
- Prompt diagnosis is essential for effective treatment and public health.
- Identifying the causative agent is key to managing outbreaks.
Observation:
- A 20-month-old infant presented with a six-day history of diarrhea and vomiting.
- Blood, stool, and urine samples were collected for analysis.
- The infant had concurrent infections with Shigella sonnei and Vibrio cholerae.
Findings:
- Concurrent infection with Shigella sonnei and Vibrio cholerae was confirmed as the cause of the infant's infectious diarrhea.
- This dual infection is infrequently observed.
- The microbiology laboratory played a vital role in pathogen detection.
Implications:
- This case underscores the importance of comprehensive microbiological investigations in pediatric infectious diarrhea.
- Understanding the pathogenesis and diagnostic methods for Shigella sonnei and Vibrio cholerae is crucial.
- Early and accurate identification of rare enteric pathogens aids in preventing disease spread and improving patient outcomes.
Abstract:
A 20-month-old infant presented to the emergency department with diarrhea and vomiting of six days duration. Blood, stool and urine specimens were collected for both bacteriological culture and parasitic workup. Concurrent infections with both Shigella sonnei and Vibrio cholerae were determined to be the cause of the infectious diarrhea. This case illustrates the importance of the microbiology laboratory in detecting infrequently seen enteric pathogens. We will also review the pathogenesis and laboratory diagnosis of Vibrio cholerae and Shigella sonnei.
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