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Cognitive behavioral therapy for insomnia in euthymic bipolar disorder: study protocol for a randomized controlled
Mette Kvisten Steinan1, Karoline Krane-Gartiser, Knut Langsrud
1Department of Neuroscience, Norwegian University of Science and Technology (NTNU), Trondheim, Norway. mette.steinan@ntnu.no.
Trials
|January 18, 2014
Summary
Cognitive Behavioral Therapy for Insomnia (CBT-I) may improve sleep quality and mood stability in patients with bipolar disorder. This study compares CBT-I plus treatment as usual to treatment as usual alone for euthymic bipolar disorder patients with insomnia.
Area of Science:
- Psychiatry
- Sleep Medicine
- Clinical Psychology
Background:
- Bipolar disorder patients frequently experience sleep disturbances, even during euthymic phases.
- Sleep pattern changes can signal impending manic or depressive episodes.
- Cognitive Behavioral Therapy for Insomnia (CBT-I) is effective for primary insomnia, but its effects in bipolar disorder are unstudied.
Purpose of the Study:
- To compare CBT-I plus treatment as usual (TAU) against TAU alone in euthymic bipolar disorder patients with comorbid insomnia.
- To assess the impact of CBT-I on sleep quality, mood stability, and prevention of new mood episodes.
Main Methods:
- Randomized controlled trial including euthymic bipolar I or II disorder patients with insomnia confirmed by SCID-1.
- A three-week run-in phase with sleep/mood diaries, actigraphy, and polysomnography.
- An eight-week treatment phase comparing CBT-I (sleep restriction, psychoeducation, circadian stabilization, cognitive restructuring) with TAU (pharmacological and psychosocial treatments).
Main Results:
- This section is not available in the provided abstract.
Conclusions:
- This trial may establish CBT-I as a novel treatment for insomnia in bipolar disorder.
- Potential benefits include improved sleep and enhanced mood stability.
- The study aims to provide clearer insights into the nature of sleep disturbances in bipolar disorder.
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