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Published on: September 27, 2017
Effect of prolonged breast-feeding on risk of atopic dermatitis in early childhood
Soyoung Hong1, Won-Jun Choi, Ho-Jang Kwon
1Department of Environmental Health Research, Seoul Medical Center, Seoul, Republic of Korea.
Insights
Prolonged breast-feeding increases atopic dermatitis risk in young Korean children. This association was not observed in older children, indicating age-specific effects of breastfeeding on eczema development.
Area of Science:
- Pediatrics
- Allergology
- Epidemiology
Background:
- The relationship between breastfeeding and atopic disease development is debated.
- Atopic dermatitis (AD) is a common condition in childhood.
Purpose of the Study:
- To investigate the effect of breastfeeding on the prevalence of current atopic dermatitis (AD) in Korean children.
- To explore age-specific associations between breastfeeding duration and AD risk.
Main Methods:
- Cross-sectional study involving 10,383 Korean children aged 0-13 years.
- Data collected via parental questionnaires on AD history and environmental factors.
- Diagnostic criteria from the International Study of Asthma and Allergies in Childhood were used.
Main Results:
- Prolonged breastfeeding (>12 months) was a significant risk factor for AD in children aged ≤5 years (p < 0.001).
- No significant association between breastfeeding and AD was found in children >5 years of age.
- The risk of AD associated with breastfeeding was independent of parental history of atopic diseases.
Conclusions:
- Breastfeeding duration is a significant factor in the development of atopic dermatitis in young children.
- The impact of breastfeeding on AD risk is age-dependent, with prolonged breastfeeding posing a higher risk for children under five.
- Findings suggest tailored infant feeding recommendations may be beneficial for preventing AD.
Abstract:
The effect of breast-feeding on the risk of developing atopic disease remains controversial. This study is an investigation of the effect of breast-feeding on current atopic dermatitis (AD) among Korean children. This cross-sectional study of children's histories of current AD and environmental factors was completed by the subjects' parents. The subjects included 10,383 children aged 0-13 years in Seoul, Korea, in 2008. The diagnostic criteria of the International Study of Asthma and Allergies in Childhood were applied in this study. Adjustments were performed for age, gender, maternal education, smoking in the household, relocation to a new house within 1 year of birth, and parental history of atopic disease. After adjustment for confounders, age and duration of maternal education were found to be inversely associated with the prevalence of AD. Among subjects aged ≤5 years, the prevalence of AD was positively associated with the duration of breast-feeding (p < 0.001). However, there was no significant association between AD and breast-feeding among children >5 years of age. Regardless of parental history of atopic diseases, breast-feeding >12 months was a significant risk factor for AD. The effect of breast-feeding differed by age group. Prolonged breast-feeding increased the risk of AD in children <5 years of age, regardless of parental history of atopic diseases.
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