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Updated: May 3, 2026

Author Spotlight: A Reproductive Hysteroscopy Approach for Complete Endometrial Polyp Removal and Enhanced Endometrial Receptivity
Published on: August 2, 2024
[Use of misoprostol in gynaecology]
M Lesavre1, G Legendre1, H Fernandez1
1Service de gynécologie-obstétrique, CHU de Bicêtre, 78, avenue du Général-Leclerc, 94276 Le Kremlin-Bicêtre, France.
Objectives:
To assess the interest of misoprostol in gynaecology and particularly for cervical priming.
Method:
Research in PubMed in English and French about misoprostol and its use in gynaecology.
Results:
We summarized the results of 3 meta-analyses, randomized controlled trials and literature review. Results show that misoprostol did not scientifically prove a benefit for cervical priming before hysteroscopy or before intra-uterine device (IUD). Results are the same with post-menopausal or nulliparous women. It did not lead either to lower the complications but increase adverse effects.
Conclusion:
It is not indicated to use misoprostol for cervical priming in gynaecology.
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