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[Cardiovascular involvement in Behçet's disease].

A-C Desbois1, B Wechsler2, P Cluzel3

  • 1Service de médecine interne, centre de référence des maladies autoimmunes rares, groupe hospitalier Pitié-Salpêtrière, 75013 Paris, France; DHU i2B, immunopathologie, inflammation, biothérapie, université Pierre-et-Marie-Curie, Paris 6, AP-HP, 75013 Paris, France.

La Revue De Medecine Interne
|January 18, 2014
PubMed
Summary
This summary is machine-generated.

Vascular complications significantly impact Behçet

Keywords:
Atteinte cardiaqueAtteinte vasculaireBehçet's diseaseCardiac involvementMaladie de BehçetVascular involvementVasculariteVasculitis

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Area of Science:

  • Rheumatology
  • Vascular Medicine
  • Internal Medicine

Context:

  • Behçet's disease (BD) frequently involves vascular complications, affecting prognosis.
  • Vasculo-Behçet describes cases dominated by vascular issues, primarily in young men early in disease onset.

Purpose:

  • To outline the spectrum and significance of vascular manifestations in Behçet's disease.
  • To highlight the most severe vascular complications and their prognostic implications.

Summary:

  • Venous complications, including deep vein thrombosis and large vessel thrombosis (e.g., Budd-Chiari syndrome), are most common.
  • Arterial complications involve aneurysms and occlusions, with pulmonary artery aneurysms posing a high bleeding risk.
  • Cardiac issues include pericarditis, endocardial lesions, myocardial infarction, and intracardiac thrombosis, with coronary artery lesions being particularly severe.

Impact:

  • Understanding these vascular manifestations is crucial for managing Behçet's disease prognosis.
  • This review emphasizes the critical role of vascular assessment and management in Behçet's disease patients.
  • It informs treatment strategies, including the ongoing debate on anticoagulation for venous thrombosis.