Synthesis of tetracyclic chromenones via platinum(II) chloride catalysed cascade cyclization of enediyne-enones
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Updated: May 3, 2026
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Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions
Published on: July 17, 2020
Mahalingam Sivaraman1, Paramasivan T Perumal
1Organic Chemistry Division, CSIR - Central Leather Research Institute, Adyar, Chennai, 600020, Tamilnadu, India. ptperumal@gmail.com.
Abstract:
PtCl2 catalysed cascade cyclization of an enediyne-enone system to afford a tetracyclic chromenone is reported, which proceeds through two consecutive highly regioselective 6-endo-dig cyclizations in a single step with the formation of two new C-C bonds and two new rings in excellent yield. A mechanism for this transformation is proposed based on the isolated intermediates.
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