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Insights and advances in post-traumatic headache: research considerations
Teshamae S Monteith1, David Borsook
1Department of Neurology, Headache Division, University of Miami, Miller School of Medicine, 1120 NW 14th Street, 13th Floor, Miami, FL, 33136, USA, tmonteith@med.miami.edu.
Current Neurology and Neuroscience Reports
|January 18, 2014
Summary
Mild traumatic brain injury (mTBI) and concussion effects on the brain are not fully understood. This review focuses on post-traumatic headache (PTH), particularly its migraine-like form, and future research directions.
Area of Science:
- Neuroscience
- Neurology
- Traumatic Brain Injury Research
Background:
- Mild traumatic brain injury (mTBI) awareness is increasing in military and civilian sectors.
- Limited understanding exists regarding acute and chronic effects of concussion on central nervous system (CNS) structure and function.
- The pathophysiology of post-traumatic headache (PTH), a common post-concussive symptom, remains poorly understood.
Purpose of the Study:
- To review recent advances in understanding post-traumatic headache (PTH).
- To emphasize the migraine-like phenotype of PTH, which is the most disabling form.
- To discuss considerations for future research in PTH.
Main Methods:
- Literature review of recent advances in post-traumatic headache (PTH) research.
- Emphasis on studies focusing on the migraine-like phenotype of PTH.
- Discussion of diagnostic classification, advanced neuroimaging, biomarkers, and treatment strategies.
Main Results:
- Recent research highlights the migraine-like phenotype as a significant and disabling aspect of PTH.
- Advances in understanding the underlying mechanisms of PTH are emerging.
- The review synthesizes current knowledge and identifies gaps in the field.
Conclusions:
- Further research is crucial for a comprehensive understanding of PTH.
- Future studies should focus on refining diagnostic criteria for PTH.
- Integration of advanced neuroimaging, biomarkers, and novel treatments is essential for managing PTH.
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