Related Experiment Video
Updated: May 3, 2026

Studying Age-dependent Genomic Instability using the S. cerevisiae Chronological Lifespan Model
Published on: September 29, 2011
Genotypic stability
1N. C. State University Raleigh, N. C., USA.
Abstract:
A description for genotypic stability was developed based on the concept of a genotypic stability space. Environments were considered the measurement criteria. The coordinate position for a genotype was determined by the deviations of expected yield of the genotype from its yield if stable. An expression for the response of a stable genotype was developed. The relative genotypic stability measure was defined as the distance of a genotype from the center of the arrangement and presented as a measure of homeostasis. The comparative genotypic stability measure was defined as the distance between the positions of two genotypes and designed to measure the similarity of stability responses. The development permitted the testing of hypotheses with respect to stability concepts. A set of regional soybean test data was evaluated. The results for relative stability and the regression approach were comparable. Limitations for the regression approach were noted. Genotypes analyzed had different homeostatic properties. The genotypic responses to environmental stimuli appeared to be unique to genotypes and difficult to predict.
Related Concept Videos
Genetic Variation
Genes exist in different versions called alleles,...
Genetic Lingo
Hardy-Weinberg Principle
Principles of Pharmacogenetics: Types of Genetic Variants
Background and Environment Affect Phenotype
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
Pharmaceutical Alternatives: Stability-Related Therapeutic Nonequivalence

