Related Experiment Video
Updated: May 3, 2026

Determining The Electromyographic Fatigue Threshold Following a Single Visit Exercise Test
Published on: July 27, 2015
One-minute exercise is best for evaluation of postexercise exhaustion in myasthenia gravis
Shin J Oh1, Taiichi Nagai, Ferah Kizilay
1Department of Neurology, University of Alabama at Birmingham, UAB Station, Birmingham, Alabama, USA, 35294.
Introduction:
To find the best exercise duration for postexercise exhaustion by decrement (PEE-D) in myasthenia gravis (MG).
Methods:
In 32 tests in 32 MG patients, repetitive nerve stimulation was performed in the abductor digiti quinti muscle. The 3 Hz responses for 2 s were obtained with supramaximal stimulation at rest, and immediately after (PE0), 30 s after (PE30s), and 1, 2, 3, and 4 min after 10-s, 30-s, and 1-min exercises.
Results:
Compared with the decrement at rest, a significantly greater decrement was found at PE2m and PE3m after 30-s exercise, and at PE2m, PE3m, and PE4m after 1-min exercise. In 11 patients who showed a decremental response only with exercise, PEE-D was observed in 5 after 30-s exercise and in 8 after 1-min exercise.
Conclusions:
One-minute exercise is best for evaluation of PEE-D in MG.
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