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Updated: May 3, 2026

Whole-body PET/MRI of Pediatric Patients: The Details That Matter
Published on: December 19, 2017
Whole-body simultaneous positron emission tomography (PET)-MR: optimization and adaptation of MRI sequences
Kathryn J Fowler1, Jon McConathy, Vamsi R Narra
1Department of Radiology, Washington University, St. Louis, Missouri, USA.
Abstract:
The purpose of this article is to introduce the underlying challenges associated with the incorporation of magnetic resonance imaging (MRI) into the new hybrid imaging modality simultaneous positron emission tomography (PET)/MR and their impact on attenuation correction, sequence optimization, and protocol development. Many adjustments to MR sequences are necessary for optimal whole-body and fused image results.
Insights
This study explores challenges in integrating magnetic resonance imaging (MRI) with positron emission tomography (PET)/MR hybrid systems. Adjusting MRI sequences is crucial for effective attenuation correction and optimized fused imaging results.
Area of Science:
- Medical Imaging
- Hybrid Modalities
- Radiophysics
Background:
- Hybrid imaging combines modalities for enhanced diagnostic capabilities.
- Positron Emission Tomography (PET)/Magnetic Resonance Imaging (MRI) is an emerging hybrid technology.
- Integrating PET and MRI presents unique technical challenges.
Purpose of the Study:
- To outline the challenges of incorporating MRI into simultaneous PET/MR systems.
- To discuss the impact of these challenges on key imaging processes.
- To highlight the need for MR sequence optimization in PET/MR.
Main Methods:
- Review of technical considerations for PET/MR integration.
- Analysis of MRI sequence modifications for hybrid imaging.
- Discussion of attenuation correction strategies in PET/MR.
Main Results:
- Incorporating MRI into PET/MR poses challenges for attenuation correction.
- Specific adjustments to MRI sequences are required for optimal image quality.
- Protocol development for simultaneous PET/MR needs careful consideration of MRI parameters.
Conclusions:
- Successful implementation of PET/MR requires addressing MRI-related challenges.
- Optimized MRI sequences are essential for accurate PET data and fused images.
- Further research into PET/MR protocol development is warranted.
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