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Related Concept Videos

Multiple Sclerosis l: Introduction01:19

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Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...
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Mindfulness based interventions in multiple sclerosis--a systematic review.

Robert Simpson1, Jo Booth, Maggie Lawrence

  • 1General Practice and Primary Care, Institute of Health and Wellbeing, University of Glasgow, Glasgow, G12 9LX, Scotland, UK. Robert.Simpson@glasgow.ac.uk.

BMC Neurology
|January 21, 2014
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Summary
This summary is machine-generated.

Mindfulness-based interventions (MBIs) show potential benefits for multiple sclerosis (MS) patients, improving quality of life and mental health. Further research is needed to fully understand their effectiveness in the MS population.

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Area of Science:

  • Neurology
  • Psychiatry
  • Rehabilitation

Background:

  • Multiple sclerosis (MS) is a chronic, stressful condition associated with depression, anxiety, pain, and fatigue.
  • Mindfulness-based interventions (MBIs) are increasingly used in healthcare to mitigate stress and prevent depressive relapse.
  • No systematic reviews have previously evaluated MBIs specifically for individuals with MS.

Purpose of the Study:

  • To systematically review and evaluate the effectiveness of mindfulness-based interventions (MBIs) in people diagnosed with multiple sclerosis (MS).

Main Methods:

  • Systematic literature searches were conducted across seven major databases.
  • Data extraction, quality appraisal using the Cochrane Collaboration risk of bias tool, and analysis were performed independently by two reviewers.
  • Perceived stress was the primary outcome; secondary outcomes included mental health, physical health, quality of life, and health service utilization.

Main Results:

  • Three studies with 183 participants were included; studies varied in design (RCTs, controlled trial) and location (Wales, Switzerland, USA).
  • While perceived stress was not reported, significant beneficial effects were observed in quality of life (QOL), mental health (anxiety, depression), and selected physical health measures (fatigue, pain).
  • These positive effects were sustained at 3- and 6-month follow-ups, despite variable attrition rates (5-43%) and MBI durations of 6-8 weeks.

Conclusions:

  • Limited available data suggest MBIs may offer benefits for quality of life, mental health, and certain physical health aspects in MS patients.
  • Further research is necessary to determine optimal MBIs for the MS population and to clarify their long-term impact.