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Updated: May 3, 2026

Culture Methods to Determine the Limit of Detection and Survival in Transport Media of Campylobacter Jejuni in Human Fecal Specimens
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Culture Methods to Determine the Limit of Detection and Survival in Transport Media of Campylobacter Jejuni in Human Fecal Specimens

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Campylobacter coli cultured from the stools of a patient with immunoproliferative small intestinal disease

S Coeuret1, A de La Blanchardière, V Saguet-Rysanek

  • 1Infectious Diseases Unit, University of Caen, Caen, France.

Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases
|January 21, 2014
PubMed

Insights

Researchers cultured Campylobacter coli from a patient with immunoproliferative small intestinal disease (IPSID). This finding supports Campylobacter

Area of Science:

  • Gastroenterology
  • Microbiology
  • Immunology

Background:

  • Immunoproliferative small intestinal disease (IPSID) is a condition linked to Campylobacter.
  • Previous studies utilized molecular methods like 16S rDNA sequencing, in situ hybridization, and immunohistochemistry to establish this association.

Observation:

  • This study reports the successful culturing of Campylobacter from the stool of an IPSID patient for the first time.
  • Phenotypic analysis and whole genome sequencing confirmed the isolate as Campylobacter coli.

Findings:

  • Polymerase chain reaction (PCR) on an IPSID tissue biopsy confirmed the presence of Campylobacter coli.
  • The PCR test was negative for Campylobacter jejuni, another common Campylobacter species.

Implications:

  • These results provide direct microbiological evidence supporting a causative role for Campylobacter coli in IPSID.
  • This discovery may open new avenues for diagnostic and therapeutic strategies targeting Campylobacter in IPSID patients.
Keywords:
CampylobacterIPSIDimmunoproliferative small intestinal diseaselymphomaα-Heavy-chain disease

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