Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Macroamylasemia or pancreatitis? A diagnostic problem].

A Attanasio1, I Castellaro, P Rizzotti

  • 1U.S.S.L. n. 13, Regione Veneto Stabilimento Ospedaliero di Castelfranco Veneto (Treviso) Day Hospital Geriatrico.

Minerva Medica
|September 30, 1987
PubMed
Summary

Macroamylasemia, a benign condition causing high serum amylase, is often mistaken for pancreatitis. Diagnosis involves identifying large amylase molecules in the blood, not kidney issues.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical outcomes and predictors of success with Impella weaning in cardiogenic shock: a single-center experience.

Frontiers in cardiovascular medicine·2023
Same author

Motor synergies: Evidence for a novel motor signature in autism spectrum disorder.

Cognition·2021
Same author

Protein Expression of Canine and Feline Muscular Dystrophies.

Topics in companion animal medicine·2020
Same author

Endovascular Treatment of Spleno-Mesenteric-Portal Vein Thrombosis During Orthotopic Liver Transplant: 20 Years Later.

Transplantation proceedings·2020
Same author

Effects of biological factors and seasonality on the level of polycyclic aromatic hydrocarbons in red mullet (Mullus barbatus).

Environmental pollution (Barking, Essex : 1987)·2019
Same author

Photo-activated raster scanning thermal imaging at sub-diffraction resolution.

Nature communications·2019

Area of Science:

  • Clinical Biochemistry
  • Diagnostic Medicine

Background:

  • Macroamylasemia presents as elevated serum amylase due to large amylase-macromolecule complexes.
  • This benign condition is often misdiagnosed as pancreatitis, affecting 1-2% of the population.

Observation:

  • A patient with chronic liver disease and hyperamylasemia, initially suspected of pancreatitis, was evaluated.
  • The patient exhibited elevated serum amylase with normal serum lipase and urine amylase, and unimpaired renal function.

Findings:

  • Diagnostic tests including chromatography, ultracentrifugation, and electrophoresis confirmed the presence of a macromolecular amylase component in the serum.
  • The hyperamylasemia was definitively attributed to macroamylasemia, not pancreatitis.

Implications:

Related Experiment Videos

  • Recognizing macroamylasemia is crucial to avoid unnecessary investigations and misdiagnosis of pancreatic disease.
  • This case highlights the importance of specific diagnostic methods for differentiating macroamylasemia from other causes of hyperamylasemia.