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Partial hydatidiform moles: a review.

E J Watson1, E Hernandez, K Miyazawa

  • 1Department of Obstetŕics and Gynecology, Tripler Army Medical Center, Honolulu, Hawaii.

Obstetrical & Gynecological Survey
|September 1, 1987
PubMed
Summary
This summary is machine-generated.

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Partial moles, a less virulent form of molar pregnancy, share clinical traits with complete moles. Malignant sequelae can occur, necessitating follow-up with serial serum human chorionic gonadotropin (HCG) levels.

Area of Science:

  • Gynecology
  • Obstetrics
  • Reproductive Medicine

Background:

  • Partial moles represent a subtype of molar pregnancy.
  • Understanding their clinical presentation and natural progression is crucial for patient management.

Purpose of the Study:

  • To identify the clinical characteristics and natural history of partial moles.
  • To compare partial moles with complete moles regarding clinical behavior and outcomes.

Main Methods:

  • Review of three cases managed at Tripler Army Medical Center.
  • Analysis of 52 additional cases from medical literature.

Main Results:

  • Mean age at diagnosis: 25.6 years; mean gestational age: 23.8 weeks.
  • Vaginal bleeding was the most common symptom (69%).

Related Experiment Videos

  • Triploidy was the most frequent karyotype (68%); however, normal karyotypes were also observed, with some resulting in viable infant delivery.

    • Conclusions:

    • Partial moles are generally less virulent than complete moles but share similarities in clinical characteristics and natural history.
    • Malignant sequelae, such as malignant trophoblastic disease (14.5%), can occur post-evacuation.
    • Serial monitoring of serum beta-human chorionic gonadotropin (beta-HCG) is recommended for patients diagnosed with partial moles.