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Updated: May 3, 2026

Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies
Published on: January 10, 2025
Defensive functioning in MtF and FtM transsexuals
Antonio Prunas1, Roberto Vitelli2, Filomena Agnello2
1Department of Psychology, Milan-Bicocca State University, Milan, Italy; Italian Association for Sexuology and Applied Psychology (Associazione Italiana Sessuologia e Psicologia Applicata, AISPA), Milan, Italy; Personality Disorders Lab, Parma, Italy.
Abstract:
In spite of the potential clinical utility of defense mechanisms in the assessment of gender identity disorder patients as candidates to sex reassignment surgery, there is paucity of research in this field. The aim of the present study is therefore to ascertain whether the defensive profile of MtF and FtM transsexuals seeking sex reassignment surgery can be defined more primitive, immature and maladaptive than that of the two control groups. We compared the defensive profiles as assessed through the REM-71 (Steiner et al., 2001) of 104 MtF transsexuals, 46 FtM transsexuals and two control groups of males and females. Our results show that MtF transsexuals present an overall more primitive defensive array than that of both control groups, while FtMs show a profile not dissimilar from that of both control groups. Our results support the hypothesis that MtF transsexuals are characterized by higher proneness to psychopathology than the general population and show a more immature level of psychological functioning than FtM transsexuals.
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