Insomnia in paediatric chronic pain and its impact on depression and functional disability

M Kanstrup1, L Holmström, R Ringström

  • 1Behavior Medicine Pain Treatment Services, Karolinska University Hospital, Solna, Sweden; Department of Clinical Neuroscience, Karolinska Institutet, Solna, Sweden.

Insights

Insomnia significantly impacts depression and functional disability in children with chronic pain. The Insomnia Severity Index (ISI) effectively measures sleep issues in this population.

Area of Science:

  • Pediatric Health
  • Sleep Medicine
  • Pain Management

Background:

  • Chronic pain is common in children and adolescents, often co-occurring with insomnia.
  • Sleep disturbances are linked to increased depression and functional disability in pediatric chronic pain patients.
  • Further research is needed to understand the interplay between pain, insomnia, and disability in youth.

Purpose of the Study:

  • To determine the prevalence, severity, and significance of insomnia in pediatric chronic pain patients.
  • To examine insomnia's mediating role in the relationship between pain and depression/functioning.
  • To validate the Swedish translation of the Insomnia Severity Index (ISI) for use with adolescents.

Main Methods:

  • Cross-sectional correlational analysis of data from 154 pediatric chronic pain patients.
  • Patients were referred to a tertiary pain clinic.
  • Statistical evaluation of the Insomnia Severity Index (ISI) psychometric properties.

Main Results:

  • Insomnia significantly predicted variance in depression and functional disability, even after controlling for pain and demographics.
  • Insomnia demonstrated indirect effects on the relationship between pain and both depression and functional disability.
  • The Swedish ISI translation exhibited satisfactory psychometric properties, including internal consistency and concurrent validity.

Conclusions:

  • Insomnia is a critical factor in explaining depression and functional disability in pediatric chronic pain.
  • The Insomnia Severity Index (ISI) is a reliable tool for assessing insomnia in this population.
Abstract

Related Concept Videos

Insomnia01:27

Insomnia

Insomnia is a prevalent sleep disorder characterized by difficulty falling asleep, frequent awakenings during the night, and waking up too early without being able to return to sleep. People with insomnia often experience these disruptions at least three nights a week for at least one month. Chronic insomnia, which lasts for at least three months, can lead to increased anxiety, which in turn can worsen sleep difficulties, creating a cycle of sleeplessness and stress.
Multiple factors contribute...
620
Management of Insomnia01:19

Management of Insomnia

The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
785
Narcolepsy01:07

Narcolepsy

Narcolepsy is a chronic sleep disorder characterized by pervasive, uncontrolled sleepiness and other sleep disturbances. One of its hallmark symptoms is an abrupt transition to REM sleep upon falling asleep, which causes symptoms typically associated with this phase to occur unexpectedly during wakefulness. These include the following symptoms, which typically last from a minute or two to half an hour.
891
CNS Depressants: Barbiturates and Benzodiazepines01:14

CNS Depressants: Barbiturates and Benzodiazepines

CNS depressants include drugs from the category of barbiturates and benzodiazepines. They are valuable medications for managing anxiety disorders and insomnia. Barbiturates, once used to induce and maintain sleep, have been replaced mainly by benzodiazepines due to barbiturate's toxicity, tolerance, and overdose risks. They interact with GABAA receptors, leading to sedation at low doses and potentially coma and death at higher doses. Phenobarbital, a long-acting barbiturate, possesses...
1.9K
Insufficient Sleep and Sleep Deprivation01:13

Insufficient Sleep and Sleep Deprivation

Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
1.4K
Nightmares and Night Terrors01:18

Nightmares and Night Terrors

Nightmares and night terrors represent two distinct types of sleep disturbances that differ in timing, characteristics, and the sleeper's recall of the event. Nightmares are vivid, disturbing dreams that usually awaken the sleeper from REM sleep, a stage of sleep where brain activity is high, and dreams are most frequent. Upon awakening, individuals often have detailed recollections of their nightmares, which can include themes of threats to survival, security, or self-esteem.
Nightmares...
1.0K