Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Test Cross01:39

Test Cross

44.4K
Alleles are different forms of the same gene. Humans and other diploid organisms inherit two alleles of every gene, one from each parent.
44.4K
Law of Segregation01:49

Law of Segregation

78.5K
When crossing pea plants, Mendel noticed that one of the parental traits would sometimes disappear in the first generation of offspring, called the F1 generation, and could reappear in the next generation (F2). He concluded that one of the traits must be dominant over the other, thereby causing masking of one trait in the F1 generation. When he crossed the F1 plants, he found that 75% of the offspring in the F2 generation had the dominant phenotype, while 25% had the recessive phenotype.
78.5K
Trihybrid Crosses02:27

Trihybrid Crosses

26.2K
Trihybrid Crosses
Some of Mendel’s crosses examined three pairs of contrasting characteristics. Such a cross is called a trihybrid cross. A trihybrid cross is a combination of three individual monohybrid crosses. For example, plant height (tall vs. short), seed shape (round vs. wrinkled), and seed color (yellow vs. green).
The F1 generation plants of a trihybrid cross are heterozygous for all three traits and produce eight gametes. Upon self-fertilization, these gametes have an equal...
26.2K
Monohybrid Crosses01:20

Monohybrid Crosses

240.1K
Overview
240.1K
Dihybrid Crosses01:18

Dihybrid Crosses

81.8K
Overview
81.8K
Incomplete Dominance01:43

Incomplete Dominance

30.5K
Gregor Mendel's work (1822 - 1884) was primarily focused on pea plants. Through his initial experiments, he determined that every gene in a diploid cell has two variants called alleles inherited from each parent. He suggested that amongst these two alleles, one allele is dominant in character and the other recessive. The combination of alleles determines the phenotype of a gene in an organism.
30.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Automatic detection of early gastric cancer in endoscopy based on Mask region-based convolutional neural networks (Mask R-CNN)(with video).

Frontiers in oncology·2022
Same author

Development and validation of a pyradiomics signature to predict initial treatment response and prognosis during transarterial chemoembolization in hepatocellular carcinoma.

Frontiers in oncology·2022
Same author

Natural Course for Retinal Detachment in Morning Glory Disc Anomaly Based on a Grading System.

Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)·2022
Same author

Heterogeneity of T cells and macrophages in chlorine-induced acute lung injury in mice using single-cell RNA sequencing.

Inhalation toxicology·2022
Same author

Predictive Value of the Hepatic Immune Predictive Index for Patients with Primary Liver Cancer Treated with Immune Checkpoint Inhibitors.

Digestive diseases (Basel, Switzerland)·2022
Same author

Secure OFDM-PON using three-dimensional selective probabilistic shaping and chaos.

Optics express·2022
Same journal

Modeling a mixture of ordinal and continuous repeated measures.

Journal of statistical computation and simulation·2026
Same journal

Limitations of Clustering with PCA and Correlated Noise.

Journal of statistical computation and simulation·2024
Same journal

A comparative study of two-sample tests for interval-censored data.

Journal of statistical computation and simulation·2024
Same journal

Multiple imputation of missing data with skip-pattern covariates: a comparison of alternative strategies.

Journal of statistical computation and simulation·2024
Same journal

Nonmyopic and pseudo-nonmyopic approaches to optimal sequential design in the presence of covariates.

Journal of statistical computation and simulation·2023
Same journal

Stochastic gradient Langevin dynamics with adaptive drifts.

Journal of statistical computation and simulation·2022
See all related articles

Related Experiment Video

Updated: Feb 23, 2026

Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR
06:18

Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR

Published on: July 11, 2025

942

Fence Methods for Backcross Experiments.

Thuan Nguyen1, Jie Peng2, Jiming Jiang2

  • 1Department of Public Health and Preventive Medicine, Oregon Health and Science University, Portland, OR 97239, U.S.A.

Journal of Statistical Computation and Simulation
|January 21, 2014
PubMed
Summary
This summary is machine-generated.

The fence method offers a unified approach for identifying multiple quantitative trait loci (QTL), outperforming modified Bayesian Information Criterion (BIC) and shrinkage methods in backcross experiments.

Keywords:
high-dimensional variable selecitonmodel selectionrestricted fence (RF)

More Related Videos

Induction and Evaluation of Inbreeding Crosses Using the Ant, Vollenhovia Emeryi
06:44

Induction and Evaluation of Inbreeding Crosses Using the Ant, Vollenhovia Emeryi

Published on: October 5, 2018

8.1K
Methods for Performing Crosses in Setaria viridis, a New Model System for the Grasses
08:35

Methods for Performing Crosses in Setaria viridis, a New Model System for the Grasses

Published on: October 1, 2013

22.4K

Related Experiment Videos

Last Updated: Feb 23, 2026

Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR
06:18

Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR

Published on: July 11, 2025

942
Induction and Evaluation of Inbreeding Crosses Using the Ant, Vollenhovia Emeryi
06:44

Induction and Evaluation of Inbreeding Crosses Using the Ant, Vollenhovia Emeryi

Published on: October 5, 2018

8.1K
Methods for Performing Crosses in Setaria viridis, a New Model System for the Grasses
08:35

Methods for Performing Crosses in Setaria viridis, a New Model System for the Grasses

Published on: October 1, 2013

22.4K

Area of Science:

  • Genetics
  • Statistical genetics
  • Bioinformatics

Background:

  • Model selection is crucial for identifying multiple genes associated with traits.
  • Information criteria like the modified Bayesian Information Criterion (BIC) are popular but have limitations.
  • Existing methods for quantitative trait loci (QTL) mapping can be complex and difficult to generalize.

Purpose of the Study:

  • To evaluate the effectiveness of the fence method for QTL mapping.
  • To compare the fence method with modified BIC and shrinkage methods in backcross experiments.
  • To demonstrate the broad applicability of the fence method.

Main Methods:

  • Simulation studies were conducted using backcross experimental data.
  • The fence method was applied to identify simultaneous susceptibility genes.
  • Performance was assessed by comparing results with modified BIC and shrinkage methods.

Main Results:

  • The fence method demonstrated robust performance in identifying multiple QTL.
  • Simulation results indicated the fence method's superiority over modified BIC in backcross designs.
  • The fence method proved more effective than popular shrinkage methods for model selection.

Conclusions:

  • The fence method provides a generalized and effective approach for QTL mapping.
  • It overcomes limitations of existing model selection criteria.
  • The fence method is a valuable tool for genetic research, particularly in backcross studies.