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Traumatic ulcerative granuloma with stromal eosinophilia
Sunira Chandra1, Srinivasa Raju2, Kunal Sah3
1Department of Oral Medicine and Radiology, Saraswati Dental College and Hospital, Faizabad Road, Lucknow, India. sunira_chandra1@yahoo.co.in.
Archives of Iranian Medicine
|January 22, 2014
Summary
Eosinophilic ulcer, a rare oral lesion, is characterized by chronic inflammation and eosinophils. Trauma is a suspected cause of this benign but persistent mouth ulcer.
Area of Science:
- Oral Pathology
- Dermatology
Background:
- Chronic oral ulcers are common, but eosinophilic ulcer (Eosinophilic ulcer or traumatic ulcerative granuloma with stromal eosinophilia - TUGSE) is a rare variant.
- TUGSE is a recently described benign oral mucosa lesion with uncertain etiopathogenesis, though trauma is implicated.
Observation:
- Clinically, TUGSE presents as a solitary ulcer with raised, indurated borders and a white or yellowish base.
- Microscopic examination reveals diffuse inflammatory infiltrate rich in eosinophils, extending into deeper muscle layers.
Findings:
- The case report details a 60-year-old female with a non-healing, painful tongue ulcer.
- Histopathological analysis confirmed the characteristics of TUGSE.
Implications:
- This case highlights the importance of recognizing TUGSE as a differential diagnosis for chronic oral ulcers.
- Further research into the etiopathogenesis of TUGSE may lead to improved diagnostic and therapeutic strategies.
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