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[Elimination of T lymphocytes from the bone marrow in HLA-incompatible bone marrow transplantation]

A Müller1, F Zintl

  • 1Universitäts-Kinderklinik und Poliklinik Jussuf Ibrahim, Jena.

Folia Haematologica (Leipzig, Germany : 1928)
|January 1, 1987
PubMed

The method presented is very well suited to eliminate T-lymphocytes from great amounts of bone-marrow. The stem cells required to reconstitute the bone-marrow are enriched in this way. It can be completely performed in a closed system. Any contamination with germs is excluded. It can be reproduced well and learnt quickly. It takes 10 hours for two trained co-workers to process 1,500 ml of bone-marrow. The vitality of cells is very good (100%). Its suitability for transplantation has still to be checked.

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