Oscillometric 24-h ambulatory blood pressure reference values in Hong Kong Chinese children and adolescents

Gabriel W K Yip1, Albert M Li, Hung-Kwan So

  • 1aDivision of Cardiology, Department of Medicine and Therapeutics bDepartment of Paediatrics cThe Nethersole School of Nursing, The Chinese University of Hong Kong, Prince of Wales Hospital dDepartment of Paediatrics, Kwong Wah Hospital eDepartment of Paediatric and Adolescent Medicine, Princess Margaret Hospital fDepartment of Paediatrics, Queen Elizabeth Hospital gDepartment of Paediatric and Adolescent Medicine, Tuen Mun Hospital, Hong Kong Special Administrative Region, Peoples' Republic of China.

Journal of Hypertension
|January 22, 2014
PubMed

Insights

This study establishes 24-hour ambulatory blood pressure monitoring (ABPM) reference values for Chinese children and adolescents. These new standards, crucial for pediatric hypertension screening, differ from previous German references.

Area of Science:

  • Pediatric Cardiology
  • Public Health
  • Biostatistics

Background:

  • Establishing accurate blood pressure (BP) reference values is critical for identifying hypertension in children.
  • Existing BP references may not accurately reflect the diverse Chinese pediatric population.

Purpose of the Study:

  • To establish community-based normal reference values for 24-hour ambulatory blood pressure monitoring (ABPM) in Chinese children and adolescents.
  • To investigate the impact of excluding overweight children on BP percentiles and compare these with German references.

Main Methods:

  • A territory-wide cross-sectional prospective cohort study involving 1445 Hong Kong Chinese children and adolescents aged 8-17 years.
  • ABPM assessment using validated oscillometric recorders, adhering to American Heart Association recommendations.
  • LMS method employed to construct reference tables, normalizing BP data by sex and age or height.

Main Results:

  • Ambulatory BP was higher in boys, with the difference widening with age.
  • Daytime and night-time systolic and diastolic BP showed increasing trends with age and height in both sexes.
  • Excluding overweight children resulted in lower age- and sex-specific 95th percentiles (up to 2.5/1 mmHg for SBP/DBP).
  • Overall and nonoverweight reference standards were generally higher than German references.

Conclusions:

  • The study provides essential sex- and age/height-specific ambulatory BP standards for Chinese children.
  • Further longitudinal studies are needed to confirm the clinical utility of these standards in the Chinese population.
Abstract

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