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Related Experiment Videos

Incidental versus manifest prostatic carcinoma.

P E Jørgensen1, N Weis, E Bruun

  • 1Department of Urology H, Gentofte Hospital, University of Copenhagen, Denmark.

International Urology and Nephrology
|January 1, 1987
PubMed
Summary

For incidental prostate cancer found during transurethral resection of the prostate (TUR-P), deferred treatment is often sufficient. This approach is supported by findings showing these cancers are well-differentiated and rarely progress to symptomatic disease.

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Area of Science:

  • Urology
  • Oncology
  • Pathology

Background:

  • Management of incidental prostate cancer remains a clinical challenge.
  • Distinguishing between incidental and manifest prostate cancer is crucial for treatment decisions.

Purpose of the Study:

  • To evaluate the clinical course of incidental prostate carcinoma diagnosed via transurethral resection of the prostate (TUR-P).
  • To compare the outcomes of incidental versus manifest prostate carcinoma.

Main Methods:

  • Retrospective study of 86 consecutive patients diagnosed with prostate carcinoma at TUR-P between 1979-1983.
  • Analysis of histological differentiation and clinical progression for incidental and manifest cases.

Main Results:

  • 17% of patients had incidental prostate carcinoma, which was significantly more well-differentiated histologically.

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  • Only one patient with incidental carcinoma required endocrine therapy, compared to 31 with manifest carcinoma (p < 0.01).
  • Conclusions:

    • The distinction between incidental and manifest prostate carcinoma is clinically justified.
    • Deferred treatment is a suitable management strategy for most patients with incidental prostate carcinoma detected by TUR-P.