Analysis of rRNA operons in Ureaplasma urealyticum

Physical maps of Ureaplasma urealyticum serotypes I and IV were obtained by differential hybridization of DNA restriction fragments to probes derived from the Escherichia coli rrnB operon. Each of the organisms contained two rRNA operons with genes linked in the typical order 5'-16S-23S-5S-3'. There was no BclI site in either of the operons, but there were several internal HindIII and EcoRI sites showing significant heterogeneity in their respective position in both of the serotypes.