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[Marfan syndrome and valvular disease]

M Pasic1, M Bauer, R Hetzer

  • 1Deutsches Herzzentrum Berlin, Klinik für Herz-, Thorax- und Gefäßchirurgie, Augustenburger Platz 1, 13353, Berlin, Germany, pasic@dhzb.de.

Zeitschrift Fur Kardiologie
|January 22, 2014
PubMed

Insights

This study reviews surgical treatments for Marfan syndrome cardiovascular complications in 243 patients. While preserving the native aortic valve is possible, long-term outcomes require further investigation.

Area of Science:

  • Cardiovascular Surgery
  • Genetics
  • Connective Tissue Disorders

Context:

  • Marfan syndrome is a hereditary connective tissue disorder.
  • Cardiovascular complications significantly increase mortality in Marfan syndrome patients.
  • Surgical intervention is crucial for managing cardiovascular manifestations.

Purpose:

  • To report surgical treatment experiences for 243 Marfan syndrome patients with cardiovascular complications.
  • To evaluate classical surgical methods (Bentall-DeBono, Cabrol) for annulo-aortic ectasia.
  • To assess the feasibility and outcomes of native aortic valve preservation and mitral valve surgery.

Summary:

  • The study details surgical interventions for annulo-aortic ectasia in Marfan syndrome.
  • Classical techniques and valve-sparing procedures were employed.
  • Mitral valve surgery was performed based on established indications.

Impact:

  • Provides insights into surgical management strategies for Marfan syndrome.
  • Highlights the potential of valve-sparing aortic root replacement.
  • Emphasizes the need for long-term follow-up on valve preservation techniques.

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