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Updated: May 3, 2026
07:34
Surgery and Sample Processing for Correlative Imaging of the Murine Pulmonary Valve
Published on: August 5, 2021
2.1K
[Marfan syndrome and valvular disease]
1Deutsches Herzzentrum Berlin, Klinik für Herz-, Thorax- und Gefäßchirurgie, Augustenburger Platz 1, 13353, Berlin, Germany, pasic@dhzb.de.
Zeitschrift Fur Kardiologie
|January 22, 2014
Summary
This study reviews surgical treatments for Marfan syndrome cardiovascular complications in 243 patients. While preserving the native aortic valve is possible, long-term outcomes require further investigation.
Area of Science:
- Cardiovascular Surgery
- Genetics
- Connective Tissue Disorders
Context:
- Marfan syndrome is a hereditary connective tissue disorder.
- Cardiovascular complications significantly increase mortality in Marfan syndrome patients.
- Surgical intervention is crucial for managing cardiovascular manifestations.
Purpose:
- To report surgical treatment experiences for 243 Marfan syndrome patients with cardiovascular complications.
- To evaluate classical surgical methods (Bentall-DeBono, Cabrol) for annulo-aortic ectasia.
- To assess the feasibility and outcomes of native aortic valve preservation and mitral valve surgery.
Summary:
- The study details surgical interventions for annulo-aortic ectasia in Marfan syndrome.
- Classical techniques and valve-sparing procedures were employed.
- Mitral valve surgery was performed based on established indications.
Impact:
- Provides insights into surgical management strategies for Marfan syndrome.
- Highlights the potential of valve-sparing aortic root replacement.
- Emphasizes the need for long-term follow-up on valve preservation techniques.
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