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Assessment of Cocaine-induced Behavioral Sensitization and Conditioned Place Preference in Mice
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Cocaine-induced changes in NMDA receptor signaling

Pavel I Ortinski1

  • 1Department of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 19104, USA, pavel.ortinski@uscmed.sc.edu.

Molecular Neurobiology
|January 22, 2014
PubMed
Summary

Cocaine exposure alters N-methyl-D-aspartate receptors (NMDARs), crucial for synaptic plasticity and addiction. This review details how cocaine impacts NMDAR expression, function, and signaling, complicating addiction research.

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