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Updated: May 3, 2026

Early Pathological and Magnetic Resonance Detection of Cerebral Injury Using a Rat Model of Neonatal Hypoxic Ischemic Encephalopathy
Published on: October 28, 2022
Teaching neuroimages: neonatal parechovirus encephalitis: typical MRI findings
Vincenzo Belcastro1, Paolo Bini, Roberta Barachetti
1From the Departments of Neurosciences (V.B.) and Neonatology (P.B., R.B., M.B.), S. Anna Hospital, Como, Italy.
Abstract:
A full-term 9-day-old girl presented with fever, irritability, and seizures. The routine CSF examination, cranial ultrasound, and laboratory tests were normal. Brain MRI showed diffuse white matter abnormality (figure). Human parechovirus (HPeV) type 3 was isolated in both CSF and blood. The neurodevelopmental outcome at 4 months is poor, and MRI shows an extensive cystic leukomalacia in the frontal white matter.
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